Download PDF by Gordon H. Baltuch, Matthew B. Stern: Deep Brain Stimulation for Parkinson's Disease

By Gordon H. Baltuch, Matthew B. Stern

ISBN-10: 0849370191

ISBN-13: 9780849370199

Thought of the biggest leap forward within the therapy of Parkinson’s illness some time past forty years, Deep mind Stimulation (DBS) is a pioneering approach of neurology and practical neurosurgery, forging huge, immense swap and development in the box. the 1st finished textual content dedicated to this surgical remedy, this resource expertly examines all facets of DBS from historical past and concept to sufferer review, restoration, and rehabilitation.  Edited by means of experts within the top-tiers of the self-discipline, together with individuals from the pioneering move disease team on the college of Pennsylvania, this article will be an necessary better half for the full neurological and neurosurgical neighborhood. an important device that lucidly covers the entire crucial components of this innovative surgical strategy, this advisor:

  • serves as a useful source and instructing consultant for sufferer evaluate and the choice of applicants for surgery
  • offers lucid descriptions of the surgical approach for STN DBS placement, reviewing either body- and frameless-based approaches
  • considers the morbidity and mortality linked to the process and information ideas for difficulty avoidance
  • discusses pre- and post-operative administration protocols, from the in depth care unit to rehabilitative settings
  • presents a scientific method of programming STN with a sequence of real-world case examples
  • broaches the tricky subject of medicine adjustment within the post-DBS sufferer for more advantageous sufferer restoration, together with illustrative case examples
  • reviews the impression of STN DBS surgical procedure on speech, stability, autonomic functionality, sleep, and weight
  • considers moral and quality-of-life matters for DBS sufferers
  • Show description

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    Additional info for Deep Brain Stimulation for Parkinson's Disease

    Example text

    Studies in the rat have suggested that STN neurons might regulate the response of GPi/SNr neurons to subsequent striatal inputs (14). STN–SNc projections may regulate DA release in the striatum (15). Subthalamo-striatal projections are scarce in comparison to those described before. In nonhuman primates, STN-to-caudate projections primarily derive from associative and limbic regions of the STN, whereas efferents to the putamen originate in the sensorimotor region (3,4,13). Afferent Projections The STN receives massive projections from the cortex, GPe, and thalamus.

    Schlaepfer TE, Lieb K. Deep brain stimulation for treatment of refractory depression. Lancet 2005; 366:1420–1422. 121. Tagliati M, Shils J, Sun C, et al. Deep brain stimulation for dystonia. Expert Rev Med Devices 2004; 1:33–41. 122. Toda H, Hamani C, Lozano A. Deep brain stimulation in the treatment of dyskinesia and dystonia. Neurosurg Focus 2004; 17:E2. 123. Visser-Vandewalle V, Ackermans L, van der Linden C, et al. Deep brain stimulation in Gilles de la Tourette’s syndrome. Neurosurgery 2006; 58:E590.

    Aouizerate B, Martin-Guehl C, Cuny E, et al. Deep brain stimulation of the ventral striatum in the treatment of obsessive-compulsive disorder and major depression. Med Sci (Paris) 2005; 21:811–813. 118. Aouizerate B, Martin-Guehl C, Cuny E, et al. Deep brain stimulation for OCD and major depression. Am J Psychiatry 2005; 162:2192. 119. Sakas DE, Panourias IG. Rostral cingulate gyrus: a putative target for deep brain stimulation in treatment-refractory depression. Med Hypotheses 2006; 66:491–494.

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    Deep Brain Stimulation for Parkinson's Disease by Gordon H. Baltuch, Matthew B. Stern


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