Download e-book for iPad: Clinical Functional MRI: Presurgical Functional Neuroimaging by Christoph Stippich

By Christoph Stippich

ISBN-10: 3662451220

ISBN-13: 9783662451229

ISBN-10: 3662451239

ISBN-13: 9783662451236

The moment, revised version of this winning textbook presents an updated description of using preoperative fMRI in sufferers with mind tumors and epilepsies. cutting-edge fMRI systems are awarded, with unique attention of functional points, imaging and knowledge processing, basic and pathological findings, and diagnostic probabilities and boundaries. proper details on mind body structure, useful neuroanatomy, imaging approach, and technique is supplied via famous specialists in those fields. in comparison with the 1st version, chapters were up to date to mirror the newest advancements and particularly the present use of diffusion tensor imaging (DTI) and resting-state fMRI. solely new chapters are incorporated on resting-state presurgical fMRI and the function of DTI and tractography in mind tumor surgical procedure. extra chapters tackle multimodality useful neuroimaging, mind plasticity, and pitfalls, advice, and tricks.

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Extra info for Clinical Functional MRI: Presurgical Functional Neuroimaging

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These beta values are compared with each other using contrasts resulting in a statistical value at each voxel. The statistical values of all voxels form a three-dimensional statistical map. To protect against wrongly declaring voxels as significant, statistical maps are thresholded properly by taking into account the multiple comparison problem. This problem is caused by the large number of independently performed statistical tests (one for each voxel). In recent years, parallel imaging techniques have been developed, which allow acquiring MRI data simultaneously with two or more receiver coils.

2) and requires randomized intertrial intervals (“jitter”), which can be easily obtained by adding “null” (baseline) trials when trial sequences are created for an experiment. Note, however, that single-trial analyses are only possible when using a slow event-related design. While adding null trials and simple ­permutations of trial types produce already good event sequences for rapid event-related designs, statistical power can be maximized by using more advanced randomization procedures (Wager and Nichols 2003; Maus et al.

For primary visual cortex (V1), Boynton et al. (1996) showed that the measured responses to stimuli with varying amplitudes and durations could be indeed predicted well from the response profile obtained from a short visual stimulus. A well-suited function to model the hemodynamic impulse function is the probability density function (pdf) of the gamma distribution scaled by parameter A: y ( x; A, τ, σ) = Ax τ / σ−1 e− x / σ σ τ / σ Γ (τ/σ) Parameters τ and σ define the onset and dispersion of the response peak, respectively.

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Clinical Functional MRI: Presurgical Functional Neuroimaging by Christoph Stippich


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