Giuseppe Lanzino's Cavernous malformations of the brain and spinal cord PDF

By Giuseppe Lanzino

ISBN-10: 1282864963

ISBN-13: 9781282864962

ISBN-10: 1588903435

ISBN-13: 9781588903433

ISBN-10: 1604064765

ISBN-13: 9781604064766

ISBN-10: 3131418915

ISBN-13: 9783131418913

This ebook provides a accomplished evaluate of the fundamental technological know-how and present medical wisdom on cavernous malformations of the mind and spinal wire. Cavernous ...

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offers info on surgical symptoms and coverings for cavernous malformations, together with cavernous angioma, cavernoma, and cavernous hemangioma. This booklet is meant for neurosurgeons and Read more...

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Extra info for Cavernous malformations of the brain and spinal cord

Example text

2 on gradient-echo sequences. Even in this highly selective population, 10% of confirmed CCM1 carriers had only one lesion on gradient-echo MR images. Eight patients (all asymptomatic carriers) had no lesions identified on T2-weighted images, emphasizing the importance of gradient-echo imaging and a careful family history in diagnosing the familial nature of CCMs in some patients. 10 Their report emphasized the variable clinical penetrance of this disorder as well as the limitations of computed tomography (CT) for the detection of these lesions.

Johnson PC, Wascher TM, Golfinos J, et al. Definition and pathologic features. In: Awad IA, Barrow DL, eds. Cavernous Malformations. Park Ridge, IL: AANS; 1993:1–11. 38. Rengachary SS, Kalyan-Raman UP. Telangiectasias and venous angiomas. ed. In: Wilkins RH, ed. Neurosurgery. New York: McGraw-Hill; 1996:2509–2514 39. Awad IA, Robinson JR Jr, Mohanty S, et al. Mixed vascular malformations of the brain: clinical and pathogenetic considerations. Neurosurgery 1993;33(2):179–188, discussion 188 40. Gomori JM, Grossman RI, Goldberg HI, et al.

11–15 In 1988, Mason and coworkers16 and Rigamonti and colleagues3 published reports confirming the autosomal dominant inheritance of CCMs in Hispanic families. 17 used linkage analysis on genetic material collected from patients in the latter study to map the affected gene, designated CCM1, to the long arm of chromosome 7. 15,18–22 Linkage to CCM1 was also identified in non-Hispanic families. Within these studies, however, were reports of many families with either weak or no clear linkage to the CCM1 locus.

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Cavernous malformations of the brain and spinal cord by Giuseppe Lanzino


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