New PDF release: Advances in Surgical Pathology: Mesothelioma

By Richard L. Attanoos

ISBN-10: 1608316181

ISBN-13: 9781608316182

Advances in Surgical Pathology: Mesothelioma, a quantity within the Advances in Surgical Pathology sequence, positive factors chapters on present and approaching adjustments within the box with an emphasis on sensible concerns, contemporary advancements, and rising concepts.

 Created as a short assessment, this quantity can provide a concise, up-to-date evaluation of the pathological features of mesothelioma—emphasizing the histologic correlation, scientific administration, and remedy of the disease.  well timed content material positive factors comprise reputation of precursor mesothelial lesions, the function of molecular biology within the analysis and analysis of mesothelioma, the interface among the clinician and the surgical pathologist, and the felony implications of attributing affliction starting place to asbestos and different elements. The booklet offers a source for the periodic updates in wisdom required for day-by-day perform, for present credentialing, and for the self-assessment modules for recertification. 

  • Concise and sensible format presents a brief evaluate of mesothelioma perfect for citizens, fellows, training pathologists, and clinicians. 
  • Core content material addresses mesothelioma prognosis, WHO class, staging, imaging, biopsy, mimicking stipulations, immunohistochemistry, specified gene treatment, and the potential of stem telephone treatment.
  • Focus on fresh advances and rising technologies is helping advisor readers’ scientific care while treating sufferers with mesothelioma.
  • Over one hundred ten full-color images enhance diagnostic accuracy.

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Sample text

CT scan alone is therefore not diagnostic, and histologic confirmation is required. Cytologic examination of pleural fluid classifies about 60% of malignant metastatic effusions; however, pleural diffuse malignant mesothelioma is not a diagnosis that can be rendered confidently in the vast majority of cases of pleural diffuse malignant mesothelioma. 3,4 Image-guided percutaneous needle biopsy of pleural thickening is a relatively safe procedure and has been shown to be superior to Abrams pleural biopsy and has largely replaced the latter approach5,6 (Fig.

Thirty-eight patients underwent EBUS, and nodal metastases were identified in 13 of 38 (34%) patients. Twenty-two EBUS-negative patients underwent surgery with nodal sampling, and there were 10 false negatives. Sensitivity and negative predictive value for EBUS were 59% and 57%, respectively. 25 reported on a prospective study of 32 consecutive patients with proven MPM who underwent endoscopic ultrasound and fine needle aspiration (EUS-FNA) of any enlarged lymph nodes. In total, 25 patients underwent fine needle aspiration and 27 patients had mediastinoscopy.

MRI was superior to CT in identifying invasion of the diaphragm (55% accuracy for CT versus 82% accuracy for MRI) and in identifying invasion of endothoracic fascia or solitary resectable foci of chest wall invasion (46% accuracy for CT versus 69% accuracy for MRI). 14 Forty-nine patients with p ­ otentially resectable disease on CT scan underwent contrast-enhanced MRI. 13,14 Entwisle et al. propose that contrast-enhanced MRI is more accurate than unenhanced MRI when used for predicting resectability.

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Advances in Surgical Pathology: Mesothelioma by Richard L. Attanoos


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